Adult stem cells to treat multiple sclerosis

Articles from Journal of Medicine and Life are provided here courtesy of Carol Davila - University Press. Autologous MSCs derived from the bone marrow of patients with multiple sclerosis exhibit the same properties as MSCs from healthy donors, in terms of proliferation, phenotype, and differentiation in vivo and immunosuppressive ability [ 20 ]. Pre-clinical studies using mouse models of MS have also demonstrated that transplanting mesenchymal stem cells can protect neurons from further damage, improve functionality of the remaining neurons and even reduce scar formation, which is a key barrier to the repair process. Hematopoietic stem cells HSCs are a type of adult stem cell made in the bone marrow , which have the ability to produce the different cells found in the blood, including immune cells. Nerve axons are the long skinny highways that transport electrical impulses from one nerve to another. For a quick overview of what stem cells are and how they could be beneficial for people with MS, watch our series of videos presented by leading stem cell researcher Professor Robin Franklin , from the MS Society Cambridge Centre for Myelin Repair. The Role of The Microbiome in Brain Health and Disease.

This can lead to neurological problems including slow reflexes. The results are part of an FDA-approved, ongoing clinical trial , with collaborations between investigators in the U. Until the trials complete in the US it not convered by US health insurance.